41�39?33?N 70�21?11?W41.65917�N 70.35306�W (41.659158, -70.353059), about halfway along the "biceps" of the Cape Cod "arm."
It is bordered by Cape Cod Bay on the north, Nantucket Sound on the south, Sandwich and Mashpee on the west and Yarmouth on the east. Barnstable is approximately seventy miles southeast of Boston