Main economic activity is agricultural in nature, sugarcane and high quality tobacco have been key.
The foundation of the city was a natural consequence of the establishment of train station constructed by "Ferrocarriles Unidos de Caibari�n", (United Railways of Caibarien) in 1864, this node connected the valley where the city now is with the port in Caibarien at the North, Santa Clara on the South, Vega Alta and Placetas west and east respectively. The valley soon gain agricultural importance with important productions of Tobacco and Sugar. Most of the biggest sugar mills in the island were located in the Camajuani region, and its productions were exported to the rest of the country and the world using this port located in the near coastal city of Caibarien