The early
inhabitants of the "Valley of the Guaduas" were the aboriginal Panche people. It was an important stop in
the road from Santa Fe to Honda, located in a small, fertile valley. The town
proper was founded on April 20, 1572 by Andrés
Díaz Venero de Leiva. It was abandoned after its foundation until December 13,
1610, when Fray Tomas de Morales