The city is served by several bus lines that have routes within the city limits, and some others that connect it to the neighbouring cities of Yerba Buena, El Manantial, Tafí Viejo, Las Talitas, Banda del Río Salí, and Alderetes.
The Teniente General Benjamín Matienzo International Airport (TUC/SANT) is the city's airport (though located 12 kilometres (7.5 mi) east of the city, in the neighboring department of Cruz Alta) serving over 290,000 passengers a year. There are daily flights to Buenos Aires,Jujuy, Santiago del Estero, Campo Arenal, the Minera Alumbrera Gold Mine, as well as international flights to Santa Cruz de la Sierra,Bolivia. The Mauricio Gilli Aerodrome is a Private Airport, located 16 kilometres (9.9 mi) west from the city, for Private Aviation. It is locally known as Aeroclub.
There are two weekly railway service to the Retiro station in Buenos Aires, departing from the Ferrocarril Bartolomé Mitre station located near downtown (in Plaza Alberdi).
San Miguel de Tucumán enjoys one of the largest bus stations in Argentina. The 30,000 m2estación central de ómnibus opened in 1994) is the point from where hundreds of bus services arrive from and depart to almost all of the largest and mid-size cities throughout the