From the west, Gatlinburg can be reached by either US 441 (from Knoxville) or US 411 and US 321 (from Marysville).
From the south US 441 passes through the heart of the Smokies, bringing in traffic from Cherokee, NC. It is about 35 miles from Cherokee to Gatlinburg, but the high volume of tourist traffic on the road can make the trip at least an hour long.
From the east US 321 brings in traffic directly from I-40 coming in from North Carolina.
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