exit “Requejada”, go ahead to Barreda, turn right on road CA-131 to Santillana del Mar, or exit “Puente San Miguel” and take the CA-133 road to Santillana del Mar.
From Asturias: take the “Autovía Del Cantábrico” (Cantabrian Highway) or N-634 to Puente San Miguel, then the CA-133 road to Santillana del Mar.
from Madrid, Bilbao, Burgos, Palencia or Valladolid: take the highway to Torrelavega, then as above