lled by Timoleon in 345 BC. The long series of internal struggles had weakened Syracuse's power on the island, and Timoleon tried to remedy this, defeating the Carthaginians in 339 BC near the Krimisos river. But the struggle among the city's parties restarted after his death and ended with the rise of another tyrant, Agathocles, who seized power with a coup in 317 BC. He resumed the war against Carthage, with alternate fortunes. However he scored a moral success, bringing the war to the Carthaginians' native African soil, inflicting heavy losses to the enemy. The war ended with another treaty of peace which did not prevent the Carthaginians interfering in the politics of Syracuse after the death of Agathocles (289 BC). The citizens called Pyrrhus of Epirus for help. After a brief period under the rule of Epirus, Hiero II seized power in 275 BC.
Hiero inaugurated a period of 50 years of peace and prosperity, in which Syracause became one of the most renowned capitals of Antiquity. He issued the so-called Lex Hieronica, which was later adopted by the Romans for their administration of Sicily; he also had the theatre enlarged and a new immense altar, the "Hiero's Ara", built. Under his rule lived the most famous Syracusan, the mathematician and natural philosopher Archimedes. Among his many inventions were various military engines including the claw of Archimedes, later used to resist the Roman siege of 214 BC–212 BC. Literary figures included Theocritus and others.
Hiero's successor, the young Hieronymus (ruled from 215 BC), broke the alliance with the Romans after their defeat at the Battle of Cannae and accepted Carthage's support. The Romans, led by consul Marcus Claudius Marcellus, besieged the city in 214 BC. The city held out for three years, but fell in 212 BC. It is believed to have fallen due to a peace party opening a small door in the wall to negotiate a peace, but the Romans charged through the door and took the city, killing Archimedes
