Hama has become known as a center of the anti-Ba'ath opposition in Syria, most notably the Muslim Brotherhood. The city was raided by the Syrian Army, beginning with the 1964 Islamic uprising, and becoming the scene of carnage during the Islamic uprising in Syria in April 1981 and especially in 1982, when some 25,000 people were killed in what became known as Hama massacre. The city was once again besieged by the Syrian military, as one of the main arenas of the 2011 uprising