Lake St. Lucia (Lake Saint Lucia) is an estuarine lake system in northern KwaZulu-Natal, South Africa. It is the largest estuarine lake in Southern Africa, covering an area of approximately 350 km , and falls within the iSimangaliso Wetland Park (a World Heritage Site). The lake was named Santa Lucia by Manuel Perestrerello on 13 December 1575, the day of the feast of Saint Lucy. It was later renamed to St. Lucia